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FLASH GENE
Symbol ZNF354A contributors: - updated : 14-03-2003
HGNC name zinc finger protein 354A
HGNC id 11628
Location 5q35.3      Physical location : 178.138.530 - 178.157.703
Synonym name transcription factor 17
Synonym symbol(s) KID1, TCF17, HKL1, EZNF
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text clustered with ZNF354B and ZNF354C
STRUCTURE 19.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - - 2500 69.3 605 - -
- - 4300
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a N terminal Krüppel-associated (KRAB) A and B,and C terminal Krüppel-type zinc finger motifs,containing a nuclear localization signal (NLS),a PEST sequence and a RAF homology domain
conjugated MetalloP
HOMOLOGY
interspecies homolog to murine transcription factor Tcf17
homolog to rattus Kid1
Homologene
FAMILY
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,chromatin/chromosome
basic FUNCTION transcriptional repressor
CELLULAR PROCESS nucleotide, transcription, regulation
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA binding
RNA
small molecule metal binding,
Zn2+
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS