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FLASH GENE
Symbol ZNF330 contributors: - updated : 14-03-2003
HGNC name zinc finger protein 330
HGNC id 15462
Location 4q31.1-q31.2      Physical location : 142.142.048 - 142.155.848
Synonym name
  • nuclear cysteine-rich protein
  • zinc finger autoantigen 330
  • nucleolar autoantigen 36
  • Synonym symbol(s) NOA36, HSA6591
    DNA
    TYPE functioning gene
    STRUCTURE 13.00 kb     9 Exon(s)
    text structure multiple putative transcription initiation sites and no TATA box
    MAPPING cloned Y linked N status provisional
    Physical map
    SLC7A11 4q28-q32 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 LOC152594 4q28.3 similar to ART-4 protein CCRN4L 4q28.3 CCR4 carbon catabolite repression 4-like (S. cerevisiae) ELF2 4q28 E74-like factor 2 (ets domain transcription factor) LOC389224 4 hypothetical gene supported by AK097799 OSAP 4q31.1 ovary-specific acidic protein NDUFC1 4q28.2-q28.3 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa TBDN100 4q31.1 transcriptional coactivator tubedown-100 RAB33B 4q28 RAB33B, member RAS oncogene family SET7 4q28 SET domain-containing protein 7 MGST2 4q28-q31 microsomal glutathione S-transferase 2 MAML3 4q28 mastermind-like 3 (Drosophila) SCOC 4q28.3 short coiled-coil protein LOC391702 4 similar to ribosomal protein L14; 60S ribosomal protein L14 CLGN 4q28.3-q31.1 calmegin LOC152586 4q31.1 similar to RIKEN cDNA 4933434I20 MGC10084 4q31.1 hypothetical protein MGC10084 UCP1 4q28-q31 uncoupling protein 1 (mitochondrial, proton carrier) KIAA0882 4q31.1 KIAA0882 protein LOC389225 4 LOC389225 LOC389226 4 similar to ring finger protein 130; g1-related zinc finger protein RNF150 4q31.1 ring finger protein 150 LOC389227 4 LOC389227 ZNF330 4q31.1-q31.2 LOC389227 LOC389228 4 similar to GRIK2 protein IL15 4q31 interleukin 15 INPP4B 4q31.11 inositol polyphosphate-4-phosphatase, type II, 105kDa USP38 4q31.1 ubiquitin specific protease 38 GAB1 4q31.4-q13.5 GRB2-associated binding protein 1 SMARCA5 4q31.1-q31.2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 LOC389229 4 similar to Beta-glucuronidase precursor (Beta-G1) LOC166752 4q31.1 similar to embryonic blastocoelar extracellular matrix protein precursor GYPE 4q31 glycophorin E LOC152891 4q31.1 similar to WW45 protein GYPB 4q28-q31 glycophorin B (includes Ss blood group) GYPA 4q28.2-31.1 glycophorin A (includes MN blood group) LOC391703 4 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) HHIP 4q28-q32 hedgehog interacting protein
    regionally located at the site of FRA4C locus
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal localization signal (NLS)
  • nine cysteine X-X cysteine motifs of zinc finger type
  • a C terminal poly-acidic region
  • conjugated MetalloP
    HOMOLOGY
    interspecies ortholog to highly conserved genes from C.elegans to human
    Homologene
    FAMILY NOA36 family
    CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,centromere
    intracellular,nucleus,nucleolus
    text RNA-dependent nucleolar localization in interphase associated with centromeres at mitosis,and midbodies at cytokinesis
    basic FUNCTION cell-cycle control and transcriptional regulation
    CELLULAR PROCESS cell cycle
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    autoimmune antigen in a patient suffering from rhumatoid arthritis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS