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FLASH GENE
Symbol ZNF330 contributors: - updated : 14-03-2003
HGNC name zinc finger protein 330
HGNC id 15462
Location 4q31.1-q31.2      Physical location : 142.142.048 - 142.155.848
Synonym name
  • nuclear cysteine-rich protein
  • zinc finger autoantigen 330
  • nucleolar autoantigen 36
  • Synonym symbol(s) NOA36, HSA6591
    DNA
    TYPE functioning gene
    STRUCTURE 13.00 kb     9 Exon(s)
    text structure multiple putative transcription initiation sites and no TATA box
    MAPPING cloned Y linked N status provisional
    regionally located at the site of FRA4C locus
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal localization signal (NLS)
  • nine cysteine X-X cysteine motifs of zinc finger type
  • a C terminal poly-acidic region
  • conjugated MetalloP
    HOMOLOGY
    interspecies ortholog to highly conserved genes from C.elegans to human
    Homologene
    FAMILY NOA36 family
    CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,centromere
    intracellular,nucleus,nucleolus
    text RNA-dependent nucleolar localization in interphase associated with centromeres at mitosis,and midbodies at cytokinesis
    basic FUNCTION cell-cycle control and transcriptional regulation
    CELLULAR PROCESS cell cycle
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    autoimmune antigen in a patient suffering from rhumatoid arthritis
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS