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FLASH GENE
Symbol ZNF3 contributors: - updated : 21-07-2003
HGNC name zinc finger protein 3 (A8-51)
HGNC id 13089
Location 7q22.1      Physical location : 99.661.653 - 99.679.371
Synonym symbol(s) PP838, HF12, KOX25, ZFP113
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 13.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
ZNF498 7q22.1 zinc finger protein 498 CYP3A5 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 5 CYP3A5P1 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 1 CYP3A7 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 7 CYP3A5P2 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 CYP3A4 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A43 7q21.1 cytochrome P450, family 3, subfamily A, polypeptide 43 TRIM4 7q22-q31.1 tripartite motif-containing 4 AZGP1 7q22.1 alpha-2-glycoprotein 1, zinc LOC392078 7 hypothetical gene supported by BC022382 ZNF36 7q21.3-q22.1 zinc finger protein 36 (KOX 18) ZNF38 7q21-q22 zinc finger protein 38 ZNF3 7q22.1 zinc finger protein 3 (A8-51) COPS6 7q22.1 zinc finger protein 3 (A8-51) MCM7 7q21.3-q22.1 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) AP4M1 7q22.1 adaptor-related protein complex 4, mu 1 subunit TAF6 7q11 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa MGC40499 7q22.1 hypothetical protein MGC40499 LOC255374 7q22.1 similar to hypothetical protein MGC49416 LOC392079 7 similar to ribosomal protein L7 LOC389541 7 similar to CG14977-PA FLJ10925 7q22.1 hypothetical protein FLJ10925 GAL3ST-4 7q22 hypothetical protein FLJ10925 GPC2 7q22.1 glypican 2 (cerebroglycan) STAG3 7q22 stromal antigen 3 GATS 7q22.1 opposite strand transcription unit to STAG3 LOC392080 7 similar to opposite strand transcription unit to Stag3; Gats protein PILRB 7q22.1 paired immunoglobin-like type 2 receptor beta PILRA 7q22 paired immunoglobin-like type 2 receptor alpha
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1625 - 387 - Pannuti
- splicing 2603 - 410 - Pannutti
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Endocrinethyroid    
Nervousbrain    
Reproductivefemale systemovary   
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connective    
Epithelialsecretoryglandularendocrine 
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneT cell
cell lineage myeloid cells
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • zinc finger protein with one KRAB (Kruppel-associated box) domain
  • five tandemly arranged zinc finger motifs of the C2H2 Kruppel-type
  • conjugated MetalloP
    HOMOLOGY
    intraspecies homolog to UCP1,UCP3,highly
    Homologene
    FAMILY
  • zinc finger protein family
  • mitochondrial anion carrier protein
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in transcriptional regulation
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    text transcriptional repression
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism other G/A polymorphism promotes decrease risk of obesity in middle-age
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS