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FLASH GENE
Symbol ZNF239 contributors: npt - updated : 05-05-2009
HGNC name zinc finger protein 239
HGNC id 13031
Location 10q11.21      Physical location : 44.051.794 - 44.070.066
Synonym name
  • zinc finger protein MOK-2
  • zinc finger protein (C2H2) homologous to mouse MOK-2
  • Synonym symbol(s) MOK2, HOK2
    DNA
    TYPE functioning gene
    STRUCTURE 18.27 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    LOC389953 10 similar to Ig kappa chain V region (Z4) - human LOC389954 10 similar to poly(A) binding protein, cytoplasmic 1 LOC389955 10 similar to Zinc finger protein 43 (Zinc protein HTF6) (Zinc finger protein KOX27) MGC16291 10q11.21 hypothetical protein MGC16291 LOC389956 10 similar to ZNF37A protein LOC387659 10 LOC387659 LOC143341 10q11.21 eukaryotic translation initiation factor 3, subunit 6 interacting protein, putative pseudogene ZNF11B 10q11.2 zinc finger protein 11b (KOX 2) LOC283029 10q11.21 similar to Ras suppressor protein 1 BMS1L 10q11.21 BMS1-like, ribosome assembly protein (yeast) RET 10q11.2 ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) GALNACT-2 10q11.21 chondroitin sulfate GalNAcT-2 LOC221002 FXYD4 10q11.21 FXYD domain containing ion transport regulator 4 HNRPF 10q11.21-q11.22 heterogeneous nuclear ribonucleoprotein F LOC283031 10q11.21 hypothetical protein LOC283031 ZNF239 10q11.22-q11.23 zinc finger protein 239 LOC387660 10 hypothetical gene supported by M98474 LOC220992 10q11.21 Zinc finger protein 93 (Zinc finger protein HTF34) ZNF32 10q23-q24 zinc finger protein 32 (KOX 30) HNRPA3 10p11.1 heterogeneous nuclear ribonucleoprotein A3 LOC283034 10q11.21 hypothetical LOC283034 CXCL12 10q11.2 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) LOC387661 10 similar to ribosomal protein L9; 60S ribosomal protein L9 LOC387662 10 hypothetical gene supported by BX538120 RASSF4 10q11.21 Ras association (RalGDS/AF-6) domain family 4 C10orf10 10q11.21 chromosome 10 open reading frame 10 C10orf25 10q11.21 chromosome 10 open reading frame 25 ZNF22 10q11.2 zinc finger protein 22 (KOX 15) LOC340765 10q11.21 similar to double homeobox, 4; double homeobox protein 4 LOC387663 10 similar to cubilin; intrinsic factor-cobalamin receptor; intrinsic factor B12-receptor LOC389957 10 similar to breast cancer antigen NY-BR-1.1 LOC389958 10 similar to cubilin; intrinsic factor-cobalamin receptor; intrinsic factor B12-receptor LOC220974 10q11.21 similar to olfactory receptor GA_x54KRFPKN04-58149882-58150865
    RNA
    TRANSCRIPTS type messenger
    text Variants 1, 2, 3, and 4 encode the same isoform
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2087 51.5 458 - Ernoult-Lange (1995)
    - - 1924 51.5 458 - Ernoult-Lange (1995)
    - - 2047 51.5 458 - Ernoult-Lange (1995)
    - - 2406 51.5 458 - Ernoult-Lange (1995)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Endocrinepancreas   highly
    Nervousbrain   highly
    Reproductivefemale systembreast   
     male systemtestis  highly
    Urinarykidney   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • Krüppel zinc finger protein, with 10 tandem zinc finger motifs
  • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to murine Mok2
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    text nuclear matrix
    basic FUNCTION
  • transcriptional and post-transcriptional regulator
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA binding to ribonucleoprotein components
    small molecule
    protein
  • RBP3 (negative modulation of RBP3)
  • lamin A/C involved in transcriptionrepression
  • cell & other
    REGULATION
    repressed by fixatin
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS