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FLASH GENE
Symbol ZNF221 contributors: npt - updated : 05-05-2009
HGNC name zinc finger protein 221
HGNC id 13014
Location 19q13.31      Physical location : 44.455.396 - 44.471.752
Synonym symbol(s) MGC138186, MGC141986
DNA
TYPE functioning gene
STRUCTURE 16.36 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
text structure 4 exons coding
MAPPING cloned Y linked N status provisional
Physical map
LOC390940 19 similar to R28379_1 LOC126298 19q13.32 similar to FKSG27 MGC2508 19q13.32 hypothetical protein MGC2508 MGC51082 19q13.32 hypothetical protein MGC51082 TSLL2 19q13.32 hypothetical protein MGC51082 PLAUR 19q13.2 plasminogen activator, urokinase receptor R30953_1 19q13.32 hypothetical protein R30953_1 FLJ12886 19q13.32 hypothetical protein FLJ12886 KCNN4 19q13.2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 FLJ30469 19q13.32 hypothetical protein FLJ30469 ZNF283 19q13.32 zinc finger protein 283 ZNF404 19q13.32 zinc finger protein 404 ZNF45 19q13.2 zinc finger protein 45 (a Kruppel-associated box (KRAB) domain polypeptide) ZNF221 19q13.2 zinc finger protein 221 ZNF155 19q13.2-q13.32 zinc finger protein 155 (pHZ-96) ZNF230 19q13.2 zinc finger protein 230 ZNF222 19q13.2 zinc finger protein 222 ZNF223 19q13.2 zinc finger protein 223 ZNF284 19q13.32 zinc finger protein 284 ZNF224 19q13.2 zinc finger protein 224 ZNF255 19q13.2 zinc finger protein 255 ZNF225 19q13.2 zinc finger protein 225 ZNF234 19q13.32 zinc finger protein 234 ZNF226 19q13.2 zinc finger protein 226 ZNF227  zinc finger protein 227
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 2426 71 617 - Shannon (2003)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal KRAB (Krüppel associated box) domain
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • transcriptional regulator
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS