Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ZNF2 contributors: - updated : 25-07-2006
HGNC name zinc finger protein 2 (A1-5)
HGNC id 12991
Location 2q11.2      Physical location : 95.831.182 - 95.850.062
Synonym symbol(s) A1-5, ZNF661, Zfp661
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Endocrinepancreas    
Lymphoid/Immunespleen   highly
Nervousbrain    
Reproductivefemale systemuteruscervix highly
 male systemtestis  predominantly
Respiratoryrespiratory tracttrachea  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • zinc finger protein containing a potent N terminal transcriptional repression domain
  • the KRAB/FPB module
  • a C terminal zinc finger domain composed of 19 Krüppel-type C2H2 finger motifs
  • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to Drosophila CG18555
    Homologene
    FAMILY zinc finger protein family, C2H2 type, Krüppel-like, KR
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION potential transcriptional repressor, may be involved in transcriptional regulation
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS