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FLASH GENE
Symbol ZNF180 contributors: - updated : 10-07-2006
HGNC name zinc finger protein 180 (HHZ168)
HGNC id 12970
Location 19q13.1-q13.3      Physical location : 44.979.859 - 45.004.574
Synonym symbol(s) HHZ168
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text component of a cluster of zinc finger protein genes
STRUCTURE 24.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  highly
Endocrineparathyroid   highly
Lymphoid/Immunespleen   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal KRAB (Krüppel associated box) domain,
  • zinc finger motifs, C2H2 type, Krüppel-like
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY zinc finger protein family,C2H2 type
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION involved in DNA repair deficiencies and cellular malignancies
    CELLULAR PROCESS nucleotide, repair
    nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS