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FLASH GENE

Symbol

ZNF160

contributors: np/ - updated : 12-05-2006

HGNC name	zinc finger protein 160
HGNC id	12948

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19q13.41      Physical location : 53.569.867 - 53.606.687
Synonym name	KRAB zinc finger protein KR18
	zinc finger protein HZF5
Synonym symbol(s)	F11, HZF5, FLJ00032, HKr18, HZF5, KIAA1611, KR18, DKFZp686B16128

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	member of a cluster on 19q13
STRUCTURE	36.82 kb     7 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_033288 6 - 4219 NP_150630 - 818 - - NM_198893 7 - 4304 NP_942596 - 818 - - NM_001102603 7 - 4336 NP_001096073 - 818 - -

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Lymphoid/Immune spleen       highly   thymus       highly Urinary bladder       highly   kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Connective bone subchondral     Connective cartilage       Muscular striatum

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic monocyte

cell lineage
cell lines	monoblast cell lines
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	zinc finger protein
	C2H2 type, Krüppel-like
	one KRABA and one KRABB domain at the N terminus

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY

krueppel C2H2-type zinc-finger protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION	involved in transcriptionnal regulation
	regulator of blood cells development
	playing a role in renal development and maybe involved in the repair of the kidney

CELLULAR PROCESS	nucleotide, transcription, regulation
	cell organization/biogenesis

PHYSIOLOGICAL PROCESS

development

text	hematopoiesis

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS