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Symbol ZNF157 contributors: np - updated : 12-03-2003
HGNC name zinc finger protein 157
HGNC id 12942
Location Xp11.23      Physical location : 47.229.998 - 47.273.098
Synonym name
  • zinc finger protein (C2H2 type,Kruppel like)
  • zinc finger protein 22
    • Synonym symbol(s) HZF22
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text component of a cluster also including ZNF21,ZNF41,ZNF81
    STRUCTURE 43.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 1695 58 506 - -
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a KRAB (Krüppel associated box)
  • KRAB-A and KRAB-B domains at the N terminus
  • zinc finger motifs, C2H2 type, Krüppel-like
    • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in transcriptional repression
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS