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FLASH GENE
Symbol ZNF124 contributors: npt - updated : 21-12-2009
HGNC name zinc finger protein 124
HGNC id 12907
Location 1q44      Physical location : 247.319.202 - 247.335.318
Synonym name
  • zinc finger protein from a hepatoblastoma cell line
  • zinc finger protein 124 (HZF-16)
  • Synonym symbol(s) HZF16, ZK7, HZF-16, MGC117046
    DNA
    TYPE functioning gene
    STRUCTURE 16.12 kb     4 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    LOC255654 1q44 hypothetical protein LOC255654 TFB2M 1q44 transcription factor B2, mitochondrial FLJ32001 1q44 hypothetical protein FLJ32001 CGI-49 1q44 CGI-49 protein LOC391185 1 similar to kinesin-like protein (103.5 kD) (klp-6) ELYS 1q44 ELYS transcription factor-like protein TMBS62 SBZF3 1q44 zinc finger protein SBZF3 MGC12466 1q44 hypothetical protein MGC12466 FLJ12606 1q44 hypothetical protein FLJ12606 LOC388759 1 hypothetical gene supported by AK127619 ZNF124 1q44 zinc finger protein 124 (HZF-16) LOC391186 1 similar to Peroxisomal targeting signal 1 receptor (Peroxismore receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) LOC388760 1 similar to hypothetical ZNF-like protein LOC343165 1q44 similar to Heat shock cognate 71 kDa protein LOC391187 1 similar to putative G-protein coupled receptor VN1R5 1q44 vomeronasal 1 receptor 5 ZNF496 1q44 zinc finger protein 496 CIAS1 1q44 cold autoinflammatory syndrome 1 LOC127623 1q44 similar to olfactory receptor GA_x6K02SYYHDF-1415-2371 LOC127621 1q44 similar to olfactory receptor MOR256-12 OR2C3 1q44 olfactory receptor, family 2, subfamily C, member 3 LOC148823 1q44 LOC148823 LOC127617 1q44 similar to Olfactory receptor 5AV1 LOC343169 1q44 similar to Olfactory receptor 6F1 LOC388761 1 similar to olfactory receptor GA_x6K02T2NHDJ-9721756-9722757 LOC343170 1q44 similar to Olfactory receptor 5AY1 OR1C1 1q44 olfactory receptor, family 1, subfamily C, member 1 LOC127614 1q44 similar to seven transmembrane helix receptor LOC284532 1q44 similar to Olfactory receptor 5AT1 LOC391188 1 similar to hydroxysteroid (17-beta) dehydrogenase 7; 17 beta-hydroxysteroid dehydrogenase type VII LOC391189 1 similar to Olfactory receptor 6J2 LOC284535 1q44 similar to Olfactory receptor 11L1 BIA2 1q44 BIA2
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 2080 - 296 - Miyake,Saleh
    also called HZF16
    4 - 1674 - 289 in hematopoietic progenitor cells, increased after VEGF stimulation Saleh
  • also called ZK7
  • may inhibit apoptotic cell death in HNSCC.
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a Kruppel-associated box A-box domain at the NH2 terminus
  • seven ZNF motifs at the COOH terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • may be involved in the inhibitory effect of VEGF on apoptotic cell death in human hematopoietic cells
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS