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FLASH GENE

Symbol

ZNF114

contributors: npt - updated : 07-05-2009

HGNC name	zinc finger protein 114
HGNC id	12894

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19q13.32      Physical location : 48.774.653 - 48.790.863
Synonym name	zinc finger protein 114 (Y18)
Synonym symbol(s)	MGC17986, MGC149700

DNA

TYPE	functioning gene
STRUCTURE	16.36 kb     5 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ZNF114 5 - 2206 47.6 417 - Bellefroid (1993)

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Lymphoid

cells

System Cell Pubmed Species Stage Rna symbol Lymphoid/Immune T cell

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a KRAB (Krüppel associated box) at the N terminus
	several zinc finger motifs at the C terminus

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY	krueppel C2H2-type zinc-finger protein family
	KRAB subfamily

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION

basic FUNCTION

potential transcriptional repressor

CELLULAR PROCESS	nucleotide, transcription, regulation
	cell organization/biogenesis

PHYSIOLOGICAL PROCESS

development

text	hematopoiesis

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS