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FLASH GENE

Symbol

ZMYM5

contributors: - updated : 09-02-2007

HGNC name	zinc finger, MYM-type 5
HGNC id	13029

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	13q11-q12      Physical location : 20.397.623 - 20.437.776
Synonym name	zinc finger protein 237
	zinc finger protein 198-like 1
Synonym symbol(s)	ZNF198L1, HSPC050, ZNF237, MYM

DNA

TYPE	functioning gene
STRUCTURE	26.00 kb     6 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

Map	cen - ZMYM5 - ZMYM2 - qter

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 1532 42 382 - Sohal variant 2 - splicing 1246 - 208 - Sohal

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine thyroid         Urinary bladder       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective adipose

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		Hydrophilic
STRUCTURE

motifs/domains	a large region consisting of five cysteine-rich tandem repeats representing a novel zinc binding domain MYM (myeloproliferative and mental retardation motif)
	a stretch of hydrophobic proline-rich residues
	two SH3 binding motifs
	five nuclear localization signals (NLS)
	three putative phosphorylation sites

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY

MYM domain gene family, zinc finger protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION

unknown

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS