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FLASH GENE
Symbol ZMYM5 contributors: - updated : 09-02-2007
HGNC name zinc finger, MYM-type 5
HGNC id 13029
Location 13q11-q12      Physical location : 20.397.623 - 20.437.776
Synonym name
  • zinc finger protein 237
  • zinc finger protein 198-like 1
  • Synonym symbol(s) ZNF198L1, HSPC050, ZNF237, MYM
    DNA
    TYPE functioning gene
    STRUCTURE 26.00 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    Map cen - ZMYM5 - ZMYM2 - qter
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1532 42 382 - Sohal
    - splicing 1246 - 208 - Sohal
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinethyroid    
    Urinarybladder   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophilic
    STRUCTURE
    motifs/domains
  • a large region consisting of five cysteine-rich tandem repeats representing a novel zinc binding domain MYM (myeloproliferative and mental retardation motif)
  • a stretch of hydrophobic proline-rich residues
  • two SH3 binding motifs
  • five nuclear localization signals (NLS)
  • three putative phosphorylation sites
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY MYM domain gene family, zinc finger protein family
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS