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FLASH GENE
Symbol ZKSCAN5 contributors: np - updated : 03-03-2003
HGNC name zinc finger with KRAB and SCAN domains 5
HGNC id 12867
Location 7q22      Physical location : 99.102.272 - 99.131.444
Synonym name
  • related to zinc finger protein 84
  • zinc finger protein 95 homolog (mouse)
  • Synonym symbol(s) KIAA1015, ZFP95, FLJ39233, MGC33710
    DNA
    TYPE functioning gene
    STRUCTURE 29.00 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 4600 96.2 839 ubiquitous Dreyer
    - splicing 4200 96.2 839 ubiquitous Dreyer
    lacking exon V and KRAB-A domain
    - splicing 3800 - - testis Dreyer
    lacking exon IV, V and KRAB-A domain
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text widely with strongest expression in testis
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • SCAN box leucine-rich mediating self association and oligomerization and a KRAB Kruppel associated box at the N terminus
  • twelve highly conserved zinc finger motifs at the C terminus
  • conjugated MetalloP
    HOMOLOGY
    interspecies ortholog to murine Zfp95
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • transcriptional repressor
  • maybe involved in spermatogenesis and developmental processes
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS