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FLASH GENE
Symbol ZGLP1 contributors: mct/npt - updated : 18-05-2010
HGNC name zinc finger, GATA-like protein 1
HGNC id 37245
Location 19p13.2      Physical location : 10.415.479 - 10.420.233
Synonym name GATA like protein-1
Synonym symbol(s) GLP1, FLJ39511, FLJ39703, GLP-1
DNA
TYPE functioning gene
STRUCTURE 4.75 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 1997 - 271 - Li (2007)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
Endocrinepancreas    
Reproductivefemale systemuterus   
 male systemprostate   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text high levels in the somatic cells of the developing gonads, including Leydig cells in the testes and granulosa cells in the ovaries
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • acting as a transcriptional repressor of GATA factor function
  • critical nuclear repressor in somatic cells of the gonad that is required for germ cell development
  • involved in the activation of PAX4 (Brun 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS