basic FUNCTION
| important role in the metastasis and progression of pancreatic carcinoma (Lee 2010) |
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enhances the metastatic potential of pancreatic cancer cells, at least in part, by upregulating CXCR4 expression (Lee 2010) |
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secretory protein involved in pancreatic cancer progression and might be a potential target for the treatment of pancreatic cancer (Kim 2009) |
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promotes metastasis by regulating TLR/CXCR4 activation |
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novel role for ZG16B as a potent endothelial activator, promoting both angiogenesis and vascular permeability |
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can induce activation and maturation of DCs and activate NFKB1 by stimulating the Toll-like receptor signaling pathway |
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soluble protein involved in pancreatic tumorigenesis and metastasis, plays a role as an enhancer of tumor-infiltrating myeloid-derived suppressor cells (MDSCs) and its functional activity |
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plays a major role in Pancreatic tumor progression and metastasis by autocrine and paracrine manners |