Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ZG16 contributors: npt - updated : 20-08-2007
Location 16p13.3      Physical location : 29.789.560 - 29.791.839
Genatlas name zymogen granule protein 16
Synonym name secretory lectin ZG16
Synonym symbol(s) MGC34820
DNA
TYPE functioning gene
STRUCTURE 1.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 632 18.2 167 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon predominantly
 intestinesmall intestineileum  
 intestinesmall intestinejejunum moderately
 liver   highly
 pancreas exocrine   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a Jacalin domain
  • isoforms Precursor a 16 aa signal peptide
    HOMOLOGY
    Homologene
    FAMILY
  • jacalin lectin family
  • CATEGORY adaptor
    SUBCELLULAR LOCALIZATION extracellular
    intracellular,cytoplasm,cytosolic,granule
    text
  • stored in zymogen granules
  • basic FUNCTION
  • may act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
  • sugar
  • REGULATION
    induced by androgens
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    down-regulated in hepatocellular carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS