Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ZG16 contributors: npt - updated : 20-08-2007
Location 16p13.3      Physical location : 29.789.560 - 29.791.839
Genatlas name zymogen granule protein 16
Synonym name secretory lectin ZG16
Synonym symbol(s) MGC34820
DNA
TYPE functioning gene
STRUCTURE 1.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC388241 16 similar to PI-3-kinase-related kinase SMG-1 isoform 2; lambda/iota protein kinase C-interacting protein; phosphatidylinositol 3-kinase-related protein kinase MGC5178 16p12.1 hypothetical protein MGC5178 LOC388242 16 similar to hypothetical protein BC011981 KIAA0220 16p12.1 KIAA0220 protein LAT1-3TM 16p12 LAT1-3TM protein LOC388243 16 similar to carbonic anhydrase VA, mitochondrial precursor; carbonic anhydrase V, mitochondrial; carbonic dehydratase SPN 16p11.2 sialophorin (gpL115, leukosialin, CD43) QPRT 16q13 quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) FLJ35681 16p12.1 hypothetical protein FLJ35681 ZG16 16p12.1 zymogen granule protein 16 KIF22 16p11.2 kinesin family member 22 MAZ 16p11.2 MYC-associated zinc finger protein (purine-binding transcription factor) LOC112476 16p12.1 similar to lymphocyte antigen 6 complex, locus G5B; G5b protein; open reading frame 31 MGC4606 16p12.1 hypothetical protein MGC4606 MVP 16p11.2 major vault protein CDIPT 16p12.1 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) PSK-1 16p12.1 type I transmembrane receptor (seizure-related protein) KCTD13 16p11.2 potassium channel tetramerisation domain containing 13 LOC253982 16p12.1 hypothetical protein LOC253982 LOC124446 16p12.1 hypothetical protein BC017488 PSK 16p12.1 hypothetical protein BC017488 TAO1 16p11.2 hypothetical protein BC017488 HIRIP3 16q13 HIRA interacting protein 3 FLJ90652 16p12.1 hypothetical protein FLJ90652 DOC2A 16q13 double C2-like domains, alpha DKFZP434I2117 16p12.1 hypothetical protein DKFZp434I2117 ALDOA 16q22.2 aldolase A, fructose-bisphosphate PPP4C 16p12-p11 protein phosphatase 4 (formerly X), catalytic subunit TBX6 16p11.2 T-box 6 MGC10500 16p12.1 hypothetical protein MGC10500
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 632 18.2 167 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon predominantly
 intestinesmall intestineileum  
 intestinesmall intestinejejunum moderately
 liver   highly
 pancreas exocrine   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a Jacalin domain
  • isoforms Precursor a 16 aa signal peptide
    HOMOLOGY
    Homologene
    FAMILY
  • jacalin lectin family
  • CATEGORY adaptor
    SUBCELLULAR LOCALIZATION extracellular
    intracellular,cytoplasm,cytosolic,granule
    text
  • stored in zymogen granules
  • basic FUNCTION
  • may act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
  • sugar
  • REGULATION
    induced by androgens
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    down-regulated in hepatocellular carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS