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FLASH GENE
Symbol ZFP28 contributors: - updated : 08-07-2004
HGNC name zinc finger protein 28 homolog (mouse)
HGNC id 17801
Location 19q13.43      Physical location : 57.050.316 - 57.068.169
Synonym symbol(s) KIAA1431
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivestomach    
Reproductivefemale systembreastmammary gland  
 male systemtestis   
Urinarykidney    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal signal peptide
  • two KRAB domains
  • 14 C-terminal C2H2 zinc finger motifs
    • HOMOLOGY
    Homologene
    FAMILY krüppel C2H2-type zinc-finger protein family
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in regulation of transcription, DNA-dependent
  • may be playing a role in renal development and may also be involved in the repair of the kidney after ischemia- reperfusion or folic acid administration
  • playing a role in embryonic development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS