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FLASH GENE
Symbol ZFAND2A contributors: SGE/npt - updated : 03-06-2010
HGNC name zinc finger, AN1-type domain 2A
HGNC id 28073
Location 7p22.3      Physical location : 1.192.543 - 1.199.855
Synonym name
  • AN1-type zinc finger protein 2A
  • arsenite inducible RNA associated protein
  • Synonym symbol(s) AIRAP
    DNA
    TYPE functioning gene
    STRUCTURE 7.26 kb     5 Exon(s)
    regulatory sequence Promoter
    text structure
  • HSe sequence in the promoter (Rossi 2010)
  • MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 907 - 145 - Rossi (2010)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two AN1-type zinc fingers
  • HOMOLOGY
    interspecies homolog to murine Zfand2a (80.4pc)
    homolog to rattus Zfand2a (79.7pc)
    Homologene
    FAMILY
    CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • heat shock gene, may represent a new potential component of the protective response during fever (Rossi 2010)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • ions Zn2+
  • protein
    cell & other
    REGULATION
    Other induced at febrile temperatures and controlled by HSF1 (Rossi 2010)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS