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FLASH GENE
Symbol YY2 contributors: SGE/npt - updated : 29-06-2009
HGNC name YY2 transcription factor
HGNC id 31684
Location Xp22.12      Physical location : 21.874.104 - 21.876.845
Synonym name
  • transcription factor yin yang 2
  • zinc finger protein 631
  • Synonym symbol(s) ZNF631
    DNA
    TYPE functioning gene
    STRUCTURE 1.10 kb     1 Exon(s)
    regulatory sequence Promoter
    cytosine-phosphate-guanine/HTF
    text structure promoter CpG rich, repressed by methylation (Klar 2009)
    MAPPING cloned Y linked N status provisional
    regionally located . has evolved from a retroposed copy of YY1 gene inserted within an intron of MBTPS2 (Klar 2009)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1119 41.2 372 - Nguyen (2004)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen    
    Reproductivemale systemtestis   
    Respiratorylung    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • zinc-finger
  • HOMOLOGY
    intraspecies paralog to YY1
    Homologene
    FAMILY
  • YY transcription factor family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • regulating some promoters known to be controlled by YY1
  • acting as a transcriptional activator and repressor
  • can antagonize the negative actions exrted by YY1 (Klar 2005)
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding to some promoters known to be controlled by YY1
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS