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FLASH GENE
Symbol YIPF5 contributors: - updated : 07-03-2007
HGNC name Yip1 domain family, member 5
HGNC id 24877
Location 5q32      Physical location : 143.537.730 - 143.550.278
Synonym name
  • golgi membrane protein SB140
  • five-pass transmembrane protein localizing in the Golgi apparatus and
  • the endoplasmic reticulum 5
  • YPT-interacting protein 1 A
  • smooth muscle cell-associated protein 5
  • Synonym symbol(s) SB140, SMAP5, YIP1A, SMAP-5, FinGER5
    DNA
    TYPE functioning gene
    STRUCTURE 12.00 kb     6 Exon(s)
    regulatory sequence Promoter
    cytosine-phosphate-guanine/HTF
    text structure proximal 5'-flanking region of the gene lacks a TATA box and is highly GC rich
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver   highly
     pharynx   highly
    Nervousnerve   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    Muscularsmoothvessel highly
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Cardiovascularendothelial cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY small Rab GTPase interacting factor protein family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,organelle,Golgi
    text highest level of expression was found in coronary smooth muscle cells
    basic FUNCTION may play an important role in inflammation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with YIF1A and determines its localization to the Golgi apparatus
  • cell & other
    REGULATION
    induced by by transforming growth factor beta1
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS