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FLASH GENE
Symbol XCL2 contributors: mct/npt - updated : 10-06-2008
HGNC name chemokine (C motif) ligand 2
HGNC id 10646
Location 1q23-q25      Physical location : 168.510.004 - 168.513.235
Synonym name
  • small inducible cytokine subfamily C, member 2
  • cytokine SCM-1 beta
  • Synonym symbol(s) SCYC2, SCM-1b, SCM1B
    DNA
    TYPE functioning gene
    STRUCTURE 3.00 kb     3 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 566 12.5 114 - Park (2007)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node    
    Reproductivemale systemprostate   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymphocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • small inducible cytokine, retaining only two of the four cysteine of CC and CXC subfamilies
  • HOMOLOGY
    intraspecies homolog to XCL1
    Homologene
    FAMILY
  • small inducible cytokine, subfamily C
  • intercrine gamma family
  • CATEGORY signaling cytokine
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by in peripheral blood mononuclear cells by mitogenic stimulation
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to knee osteoarthritis
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS