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FLASH GENE
Symbol WNT9A contributors: mct - updated : 28-08-2015
HGNC name wingless-type MMTV integration site family, member 9A
HGNC id 12778
Location 1q42.13      Physical location : 228.109.164 - 228.135.676
Synonym name wingless-type MMTV integration site family, member 14
Synonym symbol(s) WNT14
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text clustered with WNT3A
STRUCTURE 29.32 kb     4 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
LOC343363 1q42.13 similar to basic transcription factor 3 LOC391171 1 similar to beta-tubulin 4Q LOC255208 1q42.13 HSA1q42.3 beta-tubulin 4Q pseudogene MGC42493 1q42.13 hypothetical protein MGC42493 MRP63P2 1q42.13 mitochondrial ribosomal protein 63 pseudogene 2 MGC15634 1q42.13 hypothetical protein MGC15634 FLJ12517 1q42.13 hypothetical protein FLJ12517 IMAGE3451454 1q42.13 SVAP1 protein MPN2 1q42.13 marapsin 2 WNT9A 1q42 wingless-type MMTV integration site family, member 9A LOC340346 1q42.13 hypothetical gene supported by AK093729; AK096776; AL117642 LOC391173 1 similar to capicua homolog WNT3A 1q42 wingless-type MMTV integration site family, member 3A DKFZp434C0923 1q42.13 hypothetical protein DKFZp434C0923 ARF1 1q42 ADP-ribosylation factor 1 C1orf35 1q42.13 chromosome 1 open reading frame 35 MRPL55 1p36.3 mitochondrial ribosomal protein L55 LOC391174 1 similar to hypothetical protein FLJ22875 GUK1 1q32-q41 guanylate kinase 1 GJA12 1q41-q42 gap junction protein, alpha 12, 47kDa LOC200205 1q42.13 hypothetical protein LOC200205 FLJ14124 1q42.13 hypothetical protein FLJ14124 KIAA1639 1q42.13 KIAA1639 protein TRIM11 1q42.13 tripartite motif-containing 11 TRIM17 1q42 tripartite motif-containing 17 HIST3H3 1q42 histone 3, H3 LOC391175 1 similar to 60S ribosomal protein L23a HIST3H2A 1q42.13 histone 3, H2a HIST3H2BB 1q42.13 histone 3, H2bb HIST3H2BA 1 histone 3, H2ba LOC149603 1q42.13 hypothetical protein LOC149603
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 1240 - 365 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines gastric cancer cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
cysteine rich,(PEX1)
conjugated GlycoP
HOMOLOGY
interspecies homolog to Drosophila wingless (Wg) segment polarity gene
homolog to murine mammary tumor virus integration site oncogene
Homologene
FAMILY WNT family
CATEGORY protooncogene , signaling
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • modulating cell fate and cell behavior during vertebrate development
  • is a temporal and spatial regulator of Indian hedgehog (IHH), a central player of skeletogenesis
  • its expression is enhanced in idiopathic carpal tunnel syndrome (ICTS)and WNT9A may be involved in VEGFA expression in ICTS
  • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • canonical Wnt/CTNNB pathway probably mediates regulation of IHH expression in prehypertrophic chondrocytes by WNT9A
  • regulation of CHST11 expression by opposing effects of arylsulfatase B on BMP4 and WNT9A
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS