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FLASH GENE
Symbol WFDC13 contributors: SGE/npt - updated : 25-03-2010
HGNC name WAP four-disulfide core domain 13
HGNC id 16131
Location 20q13.12      Physical location : 44.330.654 - 44.337.454
Synonym name
  • protease inhibitor WAP13
  • chromosome 20 open reading frame 138
  • Synonym symbol(s) WAP13, C20orf138, dJ601O1.3
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text belongs to the telomeric cluster
    STRUCTURE 6.80 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    PIGT 20q12-q13.1 phosphatidyl inositol glycan class T LOC149710 20q13.12 hypothetical LOC149710 WFDC2 20q12-q13.2 WAP four-disulfide core domain 2 WFDC6 20q13.12 WAP four-disulfide core domain 6 SPINLW1 20q12-q13.2 serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin) WFDC8 20q13.12 WAP four-disulfide core domain 8 WFDC9 20q12-q13.1 WAP four-disulfide core domain 9 WFDC10A 20q13.12 WAP four-disulfide core domain 10A RPS2L1 20q13.11 ribosomal protein S2-like 1 WFDC11 20q12-q13.1 WAP four-disulfide core domain 11 WFDC10B 20 WAP four-disulfide core domain 10B WFDC13 20q13.12 WAP four-disulfide core domain 13 LOC391253 20 similar to dJ601O1.1 (novel protein with Kunitz/Bovine pancreatic trypsin inhibitor domain) HNRPA1P3 20q13.12 heterogeneous nuclear ribonucleoprotein A1 pseudogene 3 WFDC3 20q13.12 WAP four-disulfide core domain 3 DNTTIP1 20q13.12 deoxynucleotidyltransferase, terminal, interacting protein 1 UBE2C 20q12-q13.1 ubiquitin-conjugating enzyme E2C TNNC2 20q12-q13.11 troponin C2, fast C20orf161 20q13.11 chromosome 20 open reading frame 161 PTE1 20q12-q13.1 peroxisomal acyl-CoA thioesterase ZSWIM3 20q13.12 zinc finger, SWIM domain containing 3 ZSWIM1 20q13.12 zinc finger, SWIM domain containing 1 C20orf165 20q13.12 chromosome 20 open reading frame 165 C20orf163 20q13.12 chromosome 20 open reading frame 163 PPGB 20q13.1 protective protein for beta-galactosidase (galactosialidosis) PLTP 20q12 phospholipid transfer protein C20orf67 20q13.12 chromosome 20 open reading frame 67 ZNF335 20q11.21-q13.12 zinc finger protein 335 FTLP 20q13.12 ferritin, light polypeptide pseudogene
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 1372 - 93 - Clauss (2002)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • WFDC domain or WAP signature motif
  • eight cysteines forming four disulfide bonds at the core of the protein
  • HOMOLOGY
    Homologene
    FAMILY
  • WAP-type four-disulfide core (WFDC) domain family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    text secreted
    basic FUNCTION
  • maybe functioning as a protease inhibitor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS