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FLASH GENE
Symbol WFDC11 contributors: - updated : 26-02-2004
HGNC name WAP four-disulfide core domain 11
HGNC id 20478
Location 20q12-q13.1      Physical location : 44.277.202 - 44.298.878
Genatlas name putative protease inhibitor WAP11
Synonym symbol(s) WAP11
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 21.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein
  • HOMOLOGY
    Homologene
    FAMILY WAP-type four-disulfide core (WFDC) domain family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION functioning as a protease inhibitor
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS