basic FUNCTION
| involved in cell cycle progression ,signal transduction, apoptosis and gene regulation |
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coregulator of Ca2+ dependent exocytosis of neurotransmitter |
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required for the Notch pathway |
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targeting of WDR7 significantly affected Notch signaling in several different mammalian cell types and, in particular, had a significant effect on osteoclast differentiation |
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necessary for proper Notch signaling in mammalian keratinocytes |
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likely influences Notch signaling through its involvement in the acidification of intracellular compartments via the V-ATPase complex |
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