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FLASH GENE
Symbol WDR46 contributors: np/mct - updated : 19-03-2003
HGNC name WD repeat domain 46
HGNC id 13923
Location 6p21.3      Physical location : 4.479.118 - 33.257.304
Synonym name
  • chromosome 6 open reading frame 11
  • WD repeat-containing protein BING4
  • Synonym symbol(s) BING4, C6orf11, FP221
    DNA
    TYPE functioning gene
    STRUCTURE 10.10 kb     15 Exon(s)
    MAPPING cloned Y linked N status confirmed
    regionally located at the centromeric end of MHC region
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    15 - 2065 68 610 - Mungall (2003)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen   highly
     tonsils   highly
    Skin/Tegumentskin   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • four WD40 repeats
  • HOMOLOGY
    interspecies homolog to murine Bing4
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in melanomas
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS