protein
| WW domain contained in YAP |
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binding to the WW domain of Yes kinase-associated protein by its PY motifs |
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interacting with PAX8 |
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E6-associated protein interacting protein |
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interacting with YAP1 (YAP1 enhances progesterone receptor transactivation, but YAP1 coactivation function is absolutely dependent on WBP2) |
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interaction of WBP2 with TAZ is dependent on the WW domain of TAZ and the PPXY-containing C-terminal region of WBP2 |
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acts as a transcriptional coactivator for ESR1 and progesterone receptor (PGR) |
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WBP2 is a target of the Hippo/MAP3K10, and MAP3K10 is identified as yet another rheostat in the regulation of WBP2 and its oncogenic function |
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oncogenic transcriptional co-factor that interacts, amongst others, with two other transcriptional co-activators, YAP1 and TAZ, in the Hippo pathway |