Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol VTI1A contributors: mct - updated : 28-04-2012
HGNC name vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
HGNC id 17792
Location 10q25.2      Physical location : 114.206.755 - 114.578.501
Synonym name
  • vesicle transport v-SNARE protein Vti1-like 2
  • SNARE Vti1a-beta protein
  • Synonym symbol(s) MVti1, Vti1-rp2
    DNA
    TYPE functioning gene
    STRUCTURE 371.75 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 4401 - 217 - 2001 12067063
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Respiratorylung    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two coiled-coil domains
  • HOMOLOGY
    interspecies homolog to murine Vti1a
    homolog to rattus Vti1a
    Homologene
    FAMILY
  • VTI1 family
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,organelle,endosome
    basic FUNCTION
  • protein transporter activity
  • VTI1A, VTI1B, are involved in neuronal development
  • functions at early endosomes
  • in its native form, selectively maintains spontaneous neurotransmitter release
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
  • SNARE complex containing VAMP7 and VTI1A defines a novel traffic pathway to the cell surface in both neuronal and non-neuronal cells
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • not able to bind CLINT1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS