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FLASH GENE
Symbol VPREB1 contributors: np - updated : 18-08-2007
HGNC name pre-B lymphocyte gene 1
HGNC id 12709
Location 22q11.22      Physical location : 22.599.199 - 22.599.926
Synonym name
  • immunoglobulin-like V gene
  • V(pre)B protein
  • CD179 antigen-like family member A
  • immunoglobulin iota chain
    • Synonym symbol(s) IGLVPB, IG1, VpreB, CD179A, IGVPB
    DNA
    TYPE functioning gene
    STRUCTURE 0.73 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Map see IGLV@ , IGLC@
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 641 - 145 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage pre-B cells
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Vpreb1
    Homologene
    FAMILY
  • immunoglobulin superfamily
    • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • regulating immunoglobulin gene rearrangements in the early steps of B cell differentiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS