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FLASH GENE
Symbol VAMP5 contributors: - updated : 09-03-2005
HGNC name vesicle-associated membrane protein 5 (myobrevin)
HGNC id 12646
Location 2p11.2      Physical location : 85.811.530 - 85.820.511
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive ofhousekeeping
   expressed in (based on citations)
organ(s)
cell lineage in vitro myogenesis
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an amphipathic helix which may participate in coiled coil interactions
  • a C terminal hydrophobic domain predicted to serve as a membrane anchor
  • a cytoplasmic domain responsible for its correct subcellular targeting
  • HOMOLOGY
    Homologene
    FAMILY synaptobrevin,V-SNARE protein family
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    text predominantly in the trans-Golgi network
    basic FUNCTION
  • soluble N-ethylmaleimide sensitive attachment protein receptor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text vesicular trafficking
    PATHWAY
    metabolism
    signaling
    a component
  • complex between proteins on vesicle and target membranes
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS