protein
| both BTRC and FBXW11 bind specifically to USP47, and point mutations in the TRCP WD-repeat region completely abolished USP47 binding, indicating an E3-substrate-type interaction |
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a novel beta-TTCP interactor, that regulates cell growth and survival, potentially providing a novel target for anticancer therapies |
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USP47 was identified as KATNA1-specific deubiquitinating enzyme for its stabilization |
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KIFC3 suppresses the ubiquitination and resultant degradation of CDH1 by recruiting USP47 to adherens junction (AJ), a process that may be involved in maintaining stable cell-cell adhesion in epithelial sheets |