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FLASH GENE
Symbol USP45 contributors: - updated : 17-09-2004
HGNC name ubiquitin specific protease 45
HGNC id 20080
Location 6q16.2      Physical location : 99.880.183 - 99.963.252
Synonym symbol(s) MGC14793
DNA
TYPE functioning gene
STRUCTURE 83.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned N linked N status provisional
Physical map
KIAA0776 6q16.2 glutamate receptor, ionotropic, kainate 2 FHL5 6q16.1-q16.3 four and a half LIM domains 5 LOC391953 6 similar to 40S ribosomal protein S7 (S8) GPR63 6q16.1-q16.3 G protein-coupled receptor 63 C6orf66 6q16.3 chromosome 6 open reading frame 66 KIAA1900 6q16.3 KIAA1900 C6orf167 6q16.3 chromosome 6 open reading frame 167 POU3F2 6q16 POU domain, class 3, transcription factor 2 FBXL4 6q16.1-q16.3 F-box and leucine-rich repeat protein 4 LOC389416 6 similar to oxidoreductase UCPA C6orf168 6q16.3 chromosome 6 open reading frame 168 COQ3 6q21-q22 coenzyme Q3 homolog, methyltransferase (yeast) C6orf111 6q16.3 chromosome 6 open reading frame 111 USP45 6q16.2 ubiquitin specific protease 45 LOC389417 6 similar to USP45 protein LOC389418 6 similar to Heat shock protein 67B2 CCNC 6q21 cyclin C PRDM13 6q16-q21 PR domain containing 13 GPR145 6q16-q21 G protein-coupled receptor 145 LOC391954 6 similar to Peroxiredoxin 2 (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA) (PRP) (Natural killer cell enhancing factor B) (NKEF-B) LOC391955 6 similar to Arginase II, mitochondrial precursor (Non-hepatic arginase) (Kidney-type arginase) SIM1 6q16.3-q21 single-minded homolog 1 (Drosophila) HELIC1 6q16 helicase, ATP binding 1 LOC153893 6q16-q21 Homo sapiens similar to RP42 homolog (LOC153893) on chromosome 6. DJ467N11.1 6q16.1-q16.3 dJ467N11.1  protein GRIK2 6q16.3-q21 glutamate receptor, ionotropic, kainate 2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a UCH domain
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme , regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
basic FUNCTION involved in ubiquitin-dependent protein catabolism
CELLULAR PROCESS protein, degradation
protein, ubiquitin dependent proteolysis
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS