Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol UQCRH contributors: - updated : 16-01-2006
HGNC name ubiquinol-cytochrome c reductase hinge protein
HGNC id 12590
Location 1p34.1      Physical location : 46.769.379 - 46.782.445
Synonym symbol(s) MGC111572
DNA
TYPE functioning gene
STRUCTURE 13.00 kb     4 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
MGC15668 1p34.1 hypothetical protein MGC15668 MUTYH 1p34.3-p32.1 mutY homolog (E. coli) TOE1  target of EGR1, member 1 (nuclear) TESK2 1p32 testis-specific kinase 2 LOC126661 1p34.1 hypothetical protein LOC126661 DKFZP564I122 1p34.1 DKFZP564I122 protein PRDX1 1p34.1 peroxiredoxin 1 AKR1A1 1p33-p32 aldo-keto reductase family 1, member A1 (aldehyde reductase) NASP 1p34.1 nuclear autoantigenic sperm protein (histone-binding) FLJ33084 1p34.1 hypothetical protein FLJ33084 SP192 1p34.1 hypothetical protein SP192 LOC51249 1p34.1 hypothetical protein LOC51249 IPP 1p34-p32 intracisternal A particle-promoted polypeptide MAST205 1p33 intracisternal A particle-promoted polypeptide PIK3R3 1p34.1 phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) LOC388627 1 LOC388627 TSPAN-1 1p34.1 tetraspan 1 FLJ20277 RAD54L 1p32 RAD54-like (S. cerevisiae) MUF1 1p34.1 RAD54-like (S. cerevisiae) UQCRH 1p34.1 ubiquinol-cytochrome c reductase hinge protein MGC22960 1p34 MGC22960 gene FAAH 1p35-p34 fatty acid amide hydrolase LOC391036 1 similar to vitamin D3 hydroxylase associated protein LOC388628 1 hypothetical gene supported by BC021746 OTX3 1p34.1 orthodenticle homolog 3 (Drosophila) FLJ32011 1p34.1 hypothetical protein FLJ32011 MKNK1 1p34.1 MAP kinase-interacting serine/threonine kinase 1 MOB3C ATPAF1 1p33-p32.3 ATP synthase mitochondrial F1 complex assembly factor 1 LOC374973 1p34.1 LOC374973 KIAA0494 1pter-p22.1 LOC374973 CYP4B1 1p34-p12 cytochrome P450, family 4, subfamily B, polypeptide 1 LOC388629 1 similar to cytochrome P450 4Z1 CYP4Z2P 1p34.1-p33 cytochrome P450 4Z2 pseudogene CYP4A11 1p36.1-p32.1 cytochrome P450, family 4, subfamily A, polypeptide 11 CYP4X1 1p33 likely ortholog of rat cytochrome P450 4X1 CYP4Z1 1p33 cytochrome P450 4Z1 LOC284541 1p33 similar to fatty acid omega-hydroxylase CYP4A11
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 liver   highly
Lymphoid/Immunespleen    
Nervousbrain    
Reproductivefemale systembreastmammary gland  
 female systemovary   
Respiratoryrespiratory tractlarynx   
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Uqcrh
homolog to chimpanzee LOC470500
Homologene
FAMILY UQCRH/QCR6 family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
basic FUNCTION
  • part of the mitochondrial respiratory chain that may mediate formation of the complex between cytochromes c and c1
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    related resource MITOP database
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in ovarian and breast cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS