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FLASH GENE
Symbol UQCRC1 contributors: MCT - updated : 16-01-2008
HGNC name ubiquinol-cytochrome c reductase core protein I
HGNC id 12585
Location 3p21.3      Physical location : 48.636.431 - 48.647.098
Synonym name cytochrome bc1
Synonym symbol(s) D3S3191, QCR1, UQCR1
EC.number 1.10.2.2
DNA
TYPE functioning gene
STRUCTURE 10.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
13 - 1636 - 480 - Ewing (2007)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunetonsils   highly
Reproductivefemale systemovary  highly
Skin/Tegumentskin   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatum  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY peptidase family M16/insulinase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,cytoplasm,organelle,membrane
text mitochondrial inner membrane
basic FUNCTION ferrocytochrome c oxidoreductase
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS electron transport
text aerobic respiration
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein interacting with RTN4
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
related resource MITOP database
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in breast and ovarian tumors
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS