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FLASH GENE
Symbol UNC79 contributors: mct - updated : 28-01-2016
HGNC name protein unc-79 homolog
HGNC id 19966
Location 14q32.12      Physical location : -
Synonym name KIAA1409
Synonym symbol(s) FLJ43337, KIAA1409
DNA
TYPE functioning gene
STRUCTURE 374.13 kb     50 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
50 - 8471 - 2458 - 2010 21040849
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain     Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • extracellular Ca(2+) influences neuronal excitability through the UNC79-UNC80-NALCN complex in a G protein-dependent fashion
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • UNC80 is a large protein that is necessary for the stability and function of NALCN and for bridging NALCN to UNC79 to form a functional complex
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS