SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,Golgi
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| intracellular,cytoplasm,cytosolic
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| intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
|
| intracellular,nucleus,nucleoplasm,nuclear bodies,nuclear speckles
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text
| is also a novel centrosomal protein |
basic FUNCTION
| modulator of progesterone receptor chaperoning by HSP90A1 |
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regulator for the progesterone receptor/HSP90A1 chaperoning pathway |
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may play a role in erythropoiesis in stroma cells |
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in the spleen |
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involved in cytoskeletal functions, such as cell division or exocytosis |
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molecular chaperone targeted to non-muscle myosins and is essential for cell division |
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centrosomal function for UNC45A and role in cell proliferation and tumorigenesis |
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is likely a crucial component in regulating human NK cell cytoskeletal dynamics via promoting the formation of actomyosin complexes |
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is dispensable for neuron survival but required for neurite elongation |
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is a novel and master regulator of NMII-mediated cellular processes in neurons |
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is a dynamic component of actin stress fibers and functions as a myosin chaperone |
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promotes generation of contractile actomyosin bundles through synchronized nonmuscle myosin II (NM-II) folding and filament-assembly activities |
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plays likely a role in the development of a functional intestinal system |