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FLASH GENE
Symbol UGT2B7 contributors: - updated : 26-02-2004
HGNC name UDP glycosyltransferase 2 family, polypeptide B7
HGNC id 12554
Location 4q13      Physical location : 69.962.192 - 69.978.704
Synonym symbol(s) UGT2B9,UDB7
EC.number 2.4.1.17
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 16.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
LOC391661 4 similar to UDP-glucuronosyltransferase YT521 4q13.3 splicing factor YT521-B MT2P1 4p11-q21 metallothionein 2 pseudogene 1 (processed) DESC1 4q13.3 DESC1 protein UGT2B29P 4q13 UDP glycosyltransferase 2 family, polypeptide B28 pseudogene UGT2B17 4q13 UDP glycosyltransferase 2 family, polypeptide B17 LOC345378 4q13.3 similar to UDP-glucuronosyltransferase 2B15 precursor, microsomal (UDPGT) (UDPGTH-3) (HLUG4) UGT2B15 4q13.3-q21.1 UDP glycosyltransferase 2 family, polypeptide B15 UGT2B10 4q13.3 UDP glycosyltransferase 2 family, polypeptide B10 LOC391662 4 similar to UDP-glucuronosyltransferase 2B7 precursor, microsomal (UDPGT) (3,4-catechol estrogen specific) (UDPGTH-2) LOC391663 4 similar to speckle-type POZ protein FLJ21934 4q13.3 hypothetical protein FLJ21934 LOC391664 4 similar to speckle-type POZ protein UGT2B27P 4q13 UDP glycosyltransferase 2 family, polypeptide B27 pseudogene UGT2B26P 4q13 UDP glycosyltransferase 2 family, polypeptide B26 pseudogene UGT2B7 4q13 UDP glycosyltransferase 2 family, polypeptide B7 LOC391665 4 similar to UDP-glucuronosyltransferase 2A1 precursor LOC391666 4 similar to RSDK2559 UGT2B11 4q13.3 UDP glycosyltransferase 2 family, polypeptide B11 LOC391667 4 similar to RSDK2559 UGT2B28 4q13.3 UDP glycosyltransferase 2 family, polypeptide B28 LOC391668 4 similar to RSDK2559 UGT2B25P 4q13 UDP glycosyltransferase 2 family, polypeptide B25 pseudogene UGT2B24P 4q13 UDP glycosyltransferase 2 family, polypeptide B24 pseudogene LOC389209 4 LOC389209 UGT2B4 4q13 UDP glycosyltransferase 2 family, polypeptide B4 UGT2A1 4q13 UDP glycosyltransferase 2 family, polypeptide A1 SULT1B1 4q13 sulfotransferase family, cytosolic, 1B, member 1 SULT1D1P 4q13.3 sulfotransferase family, cytosolic, 1B, member 1 STE 4q13.1 sulfotransferase, estrogen-preferring CSN1S1 4q21.1 casein alpha s1 CSN2 4q13.1-q21.1 casein beta STATH 4q11-q13 statherin HTN3 4q13 histatin 3 HTN1 4q13.3 histatin 1
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   specific
Endocrinepancreas    
Nervousbrain    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
potential promoter cis-acting elements such as OCT1,PBX1and CREBBP
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,cytoplasm,cytosolic,microsome
intracellular,nucleus
intracellular,nuclear envelope
text inner and outer nuclear membrane
basic FUNCTION
  • bile acid conjugating
  • regulating the activity of a large variety of compounds including androgens,estrogens
  • potentially involved in the overall contribution of morphine analgesia and in glucuronidation of linoleic acid diols
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS