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FLASH GENE
Symbol UGT2B7 last update : 26-02-2004
HGNC name UDP glycosyltransferase 2 family, polypeptide B7
HGNC id 12554
Location 4q13
Synonym symbol(s) UGT2B9,UDB7
EC.number 2.4.1.17
DNA RNA EXP/sub-loc PROTEIN PATHOLOGY
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 16.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
LOC391661 4 similar to UDP-glucuronosyltransferase YT521 4q13.3 splicing factor YT521-B MT2P1 4p11-q21 metallothionein 2 pseudogene 1 (processed) DESC1 4q13.3 DESC1 protein UGT2B29P 4q13 UDP glycosyltransferase 2 family, polypeptide B28 pseudogene UGT2B17 4q13 UDP glycosyltransferase 2 family, polypeptide B17 LOC345378 4q13.3 similar to UDP-glucuronosyltransferase 2B15 precursor, microsomal (UDPGT) (UDPGTH-3) (HLUG4) UGT2B15 4q13.3-q21.1 UDP glycosyltransferase 2 family, polypeptide B15 UGT2B10 4q13.3 UDP glycosyltransferase 2 family, polypeptide B10 LOC391662 4 similar to UDP-glucuronosyltransferase 2B7 precursor, microsomal (UDPGT) (3,4-catechol estrogen specific) (UDPGTH-2) LOC391663 4 similar to speckle-type POZ protein FLJ21934 4q13.3 hypothetical protein FLJ21934 LOC391664 4 similar to speckle-type POZ protein UGT2B27P 4q13 UDP glycosyltransferase 2 family, polypeptide B27 pseudogene UGT2B26P 4q13 UDP glycosyltransferase 2 family, polypeptide B26 pseudogene UGT2B7 4q13 UDP glycosyltransferase 2 family, polypeptide B7 LOC391665 4 similar to UDP-glucuronosyltransferase 2A1 precursor LOC391666 4 similar to RSDK2559 UGT2B11 4q13.3 UDP glycosyltransferase 2 family, polypeptide B11 LOC391667 4 similar to RSDK2559 UGT2B28 4q13.3 UDP glycosyltransferase 2 family, polypeptide B28 LOC391668 4 similar to RSDK2559 UGT2B25P 4q13 UDP glycosyltransferase 2 family, polypeptide B25 pseudogene UGT2B24P 4q13 UDP glycosyltransferase 2 family, polypeptide B24 pseudogene LOC389209 4 LOC389209 UGT2B4 4q13 UDP glycosyltransferase 2 family, polypeptide B4 UGT2A1 4q13 UDP glycosyltransferase 2 family, polypeptide A1 SULT1B1 4q13 sulfotransferase family, cytosolic, 1B, member 1 SULT1D1P 4q13.3 sulfotransferase family, cytosolic, 1B, member 1 STE 4q13.1 sulfotransferase, estrogen-preferring CSN1S1 4q21.1 casein alpha s1 CSN2 4q13.1-q21.1 casein beta STATH 4q11-q13 statherin HTN3 4q13 histatin 3 HTN1 4q13.3 histatin 1
RNA
TRANSCRIPTS type messenger
EXPRESSION / SUBCELLULAR LOCALIZATION
EXPRESSION (based on citations)
constitutive of
   expressed in
organ(s)
SystemOrgan 1organ 2organ 3organ 4level
Digestiveliver   specific
Endocrinepancreas    
Nervousbrain    
Urinarykidney    
tissue
SystemTissueS_TissueSs_Tissuelevel
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth,lumen,membrane
intracellular,cytoplasm,cytosolic,microsome
intracellular,nucleus
intracellular,nuclear envelope
text inner and outer nuclear membrane
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
potential promoter cis-acting elements such as OCT1,PBX1and CREBBP
conjugated GlycoP
HOMOLOGY
interspecies
 
intraspecies
 
Homologene
FAMILY
CATEGORY enzyme
basic FUNCTION
  • bile acid conjugating
  • regulating the activity of a large variety of compounds including androgens,estrogens
  • potentially involved in the overall contribution of morphine analgesia and in glucuronidation of linoleic acid diols
    • implicated in a
    process
    cellular process
    physiological
    pathway
    metabolism
    signaling
    a component
    structural
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Therapy target
    animal or cellular model