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FLASH GENE
Symbol UBE2R2 contributors: - updated : 16-09-2004
HGNC name ubiquitin-conjugating enzyme E2R 2
HGNC id 19907
Location 9p11.2      Physical location : 33.817.181 - 33.920.399
Synonym name ubiquitin-conjugating enzyme UBC3B
Synonym symbol(s) UBC3B, CDC34B, FLJ20419, MGC10481
DNA
TYPE functioning gene
STRUCTURE 100.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemovary   
 male systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
UBC catalytic domain
HOMOLOGY
interspecies homolog to murine Ube2r2
homolog to rattus LOC299677
Homologene
FAMILY E2 ubiquitin-conjugating enzyme family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • catalyzes the attachment of ubiquitin to others proteins for proteolysis
  • enhances beta-catenin degradation as a result of its interaction with beta-TRCp
  • CELLULAR PROCESS protein, degradation
    protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with BTRC
    cell & other
    REGULATION
    Other phosphorylated by CK2
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS