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FLASH GENE
Symbol UBE2F contributors: npt - updated : 14-02-2005
HGNC name ubiquitin-conjugating enzyme E2F (putative)
HGNC id 12480
Location 2q37.3      Physical location : 238.875.699 - 238.950.676
Synonym name
  • NEDD8-conjugating enzyme
  • NEDD8 protein ligase UBE2F
  • NEDD8 carrier protein UBE2F
  • ubiquitin-conjugating enzyme E2F (homologous to C. elegans UBC6)
  • Synonym symbol(s) MGC18120, NCE2
    EC.number 6.3.2.-
    DNA
    TYPE functioning gene
    STRUCTURE 75.00 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 1366 21.1 185 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreasislet of Langerhans (obligat)  lowly
    Nervousbrainhindbraincerebellum lowly
    Reproductivefemale systemplacenta  lowly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta moderately
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • ubiquitin-conjugating enzyme family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • ligase activity
  • ubiquitin conjugation enzyme activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism other
    signaling
  • cellular protein metabolism
  • second step of the ubiquitin conjugation
  • a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS