Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TXNL4B contributors: - updated : 13-06-2007
HGNC name thioredoxin-like 4B
HGNC id 26041
Location 16q22.2      Physical location : 72.118.757 - 72.128.215
Synonym name Dim1-like protein
Synonym symbol(s) DLP, Dim2, FLJ20511
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestivepharynx   highly
Lymphoid/Immunelymph node   highly
Urinarykidney   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
secondary structure an extra alpha helix (alpha3) and a beta strand (beta5), which stabilize the protein, suggesting that they may be involved in interactions with hDim2-specific partners
HOMOLOGY
Homologene
FAMILY
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
text spliceosome complex
basic FUNCTION
  • implicated in not only cell cycle progression but also in a more specific molecular process such as pre-mRNA splicing
  • involved in pre-mRNA splicing, and participate in different multisubunit complexes and biological processes
  • required for S/G(2) transition
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacingwith the U5-102-kDa protein subunit of the spliceosome(C20orf14)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS