Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TWF1 | contributors: mct - updated : 05-04-2023 |
HGNC name | twinfilin, actin-binding protein, homolog 1 (Drosophila) |
HGNC id | 9620 |
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Location | 12q12 Physical location : 44.187.527 - 44.200.178 |
Synonym name | |
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Synonym symbol(s) | A6, MGC23788, MGC41876, PTK9 |
DNA |
TYPE | functioning gene |
STRUCTURE | 12.59 kb 9 Exon(s) |
motif | Viral sequence gene env |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | complex |
HOMOLOGY |
interspecies | homolog to murine Ptk9 |
homolog to rattus LOC315265 |
Homologene |
FAMILY | actin-binding protein ADF family |
CATEGORY | chaperone/stress |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic | |
intracellular,cytoplasm,cytoskeleton | |
intracellular,nuclear envelope |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | form a1 : 1 complex with ADP-actin-monomers |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
Other | phosphorylated on ser/thr residues |
small GTPase RAC1 and CDC42 regulate its localization |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |