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FLASH GENE
Symbol TUT7 contributors: mct - updated : 03-07-2013
HGNC name terminal uridylyl transferase 7
HGNC id 25817
Location 9q21.33      Physical location : -
Synonym name
  • PAP associated domain containing 6
  • terminal uridylyltransferase 7
  • TUTase 7
  • zinc finger, CCHC domain containing 6
  • Synonym symbol(s) PAPD6, FLJ13409, KIAA1711, ZCCHC6
    DNA
    TYPE functioning gene
    STRUCTURE 66.75 kb     27 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    27 - 5586 - 1495 - 2012 22898984
    20 - 4988 - 1259 - 2012 22898984
    27 - 5696 - 1495 - 2012 22898984
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunelymph node    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscular    
    Nervousperipherous   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text stem cells
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    interspecies homolog to murine MGC38585
    ortholog to Saccharomyces Cid1
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • nucleotidyltransferase activity
  • MTPAP, PAPD4, PAPD5, ZCCHC6, ZCCHC11, and TUT1, were found to govern 3prime nucleotide addition to miRNAs in a miRNA-specific manner
  • ZCCHC11 and ZCCHC6 redundantly control let-7 biogenesis in embryonic stem cells
  • ZCCHC6, ZCCHC11, and PAPD4 are the terminal uridylyl transferases responsible for pre-miRNA mono-uridylation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • components of the miRNA biogenesis pathway with ZCCHC11, PAPD4
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS