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FLASH GENE
Symbol TUBG2 contributors: mct - updated : 25-08-2008
HGNC name tubulin, gamma 2
HGNC id 12419
Location 17q21      Physical location : 40.811.265 - 40.819.023
Synonym name tubulin gamma-2 chain
Synonym symbol(s) MGC131994
DNA
TYPE functioning gene
SPECIAL FEATURE
text tandem with TUBG1
STRUCTURE 7.00 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 1830 51 451 - Niwa (2001)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouth   highly
Lymphoid/Immunespleen   highly
Nervousbrain   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six distinct domains clustered in the central part of primary aminoacid sequence
  • tubulin binding sites
  • HOMOLOGY
    intraspecies homolog to TUBG1
    Homologene
    FAMILY
  • tubulin family
  • CATEGORY regulatory , structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
    basic FUNCTION
  • organization of the microtubule cytoskeleton
  • CELLULAR PROCESS cell cycle, division
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • microtubule organizing center
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • BRCA1, hyperphosphorylated form
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS