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FLASH GENE
Symbol TSPAN1 contributors: - updated : 27-05-2005
HGNC name tetraspanin 1
HGNC id 20657
Location 1p34.1      Physical location : 46.640.748 - 46.651.633
Synonym symbol(s) NET-1, TSPAN-1
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     8 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon predominantly
 pancreas exocrine   lowly
 stomach   moderately
Reproductivefemale systemplacenta  lowly
 male systemprostate  highly
Urinarybladder   moderately
 kidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • four hydrophobic domains
  • two extracellular regions
  • HOMOLOGY
    Homologene
    FAMILY
  • transmembrane 4 superfamily
  • tetraspanin family
  • CATEGORY adhesion , regulatory , signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • mediating signal transduction events that play a role in the regulation of cell development, activation, growth and motility
  • CELLULAR PROCESS cell life, proliferation/growth
    cell migration & motility
    PHYSIOLOGICAL PROCESS locomotion
    text
  • cell adhesion
  • cell motility
  • PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS