basic FUNCTION
| enhancing the dendritic cells maturation process |
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with IL7, use different mechanisms to regulate human CD4(+) T cell homeostasis  |
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may be an important player in the acute phase of HIV-1 infection by creating an environment that is conducive for sustaining the small dose of the initial virus inoculum that crosses the mucosal barrier  |
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induces tight junction protein claudin-7 via NF-kappaB in dendritic cells  |
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plays an important role in extravillous trophoblast invasion and placentation in human early pregnancy  |
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potential key mediator of both the initiation and maintenance of Th2 responsiveness and thereby the allergic inflammatory cascade  |
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acts on multiple lineages, including dendritic cells (DCs), T cells, NKT cells, eosinophils, and mast cells, mediating proliferation and survival and linking innate and adaptive immune responses  |
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epithelial-derived cytokine TSLP triggers chemokinesis of resting primary human dendritic cells in a cell-autonomous manner  |
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could elicit basophil responses in both IL3/IL3R-sufficient and -deficient environments  |
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its expression may influence susceptibility to multiple allergic diseases by regulating basophil haematopoiesis  |
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may regulate basophil haematopoiesis in the bone marrow  |
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role for TSLP in promoting basophil haematopoiesis, peripheral basophilia and altering the functional capacity of basophils  |
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its antimicrobial activity is primarily mediated by the C-terminal part of the protein  |
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capable of activating dendritic cells to promote T helper (Th) 2 immune responses  |
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induces the invasion of human trophoblasts and plays a role in embryo implantation  |
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might downregulate NME1 expression via STAT3 signaling pathway, affecting TIMP1 expression in influencing trophoblast invasion |
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implicated in the development and progression of allergic diseases such as atopic dermatitis  |
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