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FLASH GENE
Symbol TSHZ2 contributors: mct - updated : 17-12-2011
HGNC name teashirt zinc finger homeobox 2
HGNC id 13010
Location 20q13.2      Physical location : 51.588.945 - 52.111.868
Synonym name
  • chromosome 20 open reading frame 17
  • zinc finger protein 218
  • teashirt family zinc finger 2
  • ovarian cancer-related protein 10-2
  • serologically defined colon cancer antigen 33 like
  • Synonym symbol(s) C20orf17, ZABC2, OVC10-2, TSH2, ZNF218, DKFZp686K2480, FLJ33887
    DNA
    TYPE functioning gene
    STRUCTURE 514.00 kb     3 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 12204 115 1034 - -
    3 - 11671 - 1031 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • five C2H2-type zinc fingers
  • homeobox DNA-binding domain
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • teashirt C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing a role in transcription
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    by hypermethylation in breast and prostate cancers
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS