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FLASH GENE
Symbol TSGA10 contributors: mct/npt - updated : 14-05-2008
HGNC name testis specific, 10
HGNC id 14927
Location 2q11.2      Physical location : 99.613.724 - 99.771.187
Synonym name testis development protein NYD-SP7
Synonym symbol(s) CEP4L
DNA
TYPE functioning gene
STRUCTURE 143.00 kb     19 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
UBE3AP1 2q11.1 ubiquitin protein ligase E3A pseudogene 1 LOC389008 2 similar to KIAA1641 protein LOC151320 2q11.2 similar to autoantigen NOR-90 COX5B 2cen-q13 cytochrome c oxidase subunit Vb ACTR1B 2q11.1-q11.2 ARP1 actin-related protein 1 homolog B, centractin beta (yeast) RNU4P2 2q11.2 RNA, U4 small nuclear pseudogene 2 (U4/14) LOC130639 2q11.2 hypothetical LOC130639 ZAP70 2q12 zeta-chain (TCR) associated protein kinase 70kDa RW1 2q11.2 RW1 protein MGC26733 2q11.2 hypothetical protein MGC26733 CNGA3 2q11.2 cyclic nucleotide gated channel alpha 3 INPP4A 2q11.2 inositol polyphosphate-4-phosphatase, type I, 107kDa GMH1 MGAT4A 2q12 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A LOC343990 2q11.2 hypothetical LOC343990 TSGA10 2q11.2 testis specific, 10 MGC29762 LIPT1 2q11.2 testis specific, 10 LOC129531 2q11.2 hypothetical protein BC018453 MRPL30 2q11.2 mitochondrial ribosomal protein L30 LYG2 2q11.2 lysozyme-like LOC129530 2q11.2 hypothetical protein LOC129530 APACD 2q11.2 ATP binding protein associated with cell differentiation IF2 2p11.1-q11.1 ATP binding protein associated with cell differentiation REV1L 2q11.1-q11.2 REV1-like (yeast) LAF4 2q11.2-q12 lymphoid nuclear protein related to AF4 LOC389009 2 LOC389009 FLJ45273 2q12.1 FLJ45273 protein HCP7 2q11.2 cytochrome c, somatic pseudogene CHST10 2p11.2 carbohydrate sulfotransferase 10 LOC129522 2q12.1 similar to RalA binding protein 1 (RalBP1) (Ral interacting protein 1) (76-kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) LOC129521 2q12.1 similar to hypothetical protein VIAF1 2q12.1 IAP-associated factor VIAF1 LOC150580 2q12.1 similar to hypothetical protein FLJ39426 LOC389010 2 LOC389010
RNA
TRANSCRIPTS type messenger
text Variants 1 and 2 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
19 - 3044 81.4 698 - Reimand (2008)
19 - 3049 81.4 698 - Reimand (2008)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis  highly
Respiratoryrespiratory tracttrachea  highly
Urinarybladder   highly
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • myosin tail
  • HOMOLOGY
    Homologene
    FAMILY
  • ezrin-radixin-moesin family
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • tumour-associated antigen of cutaneous lymphoma
  • testis-expressed protein with a key role in spermatogenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in hepatocellular carcinomas and bladder cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene target of immune reactions in autoimmune polyendocrine syndrome type I (PGA1)
    Marker
    Therapy target
    ANIMAL & CELL MODELS