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FLASH GENE
Symbol TSG10B contributors: npt - updated : 01-03-2010
Location 10q24-q26      Physical location : -
Genatlas name tumor suppressor gene(s),chromosome 10
DNA
TYPE functioning gene
MAPPING cloned   linked   status confirmed
Map cen - D10S108 - [D10S566 - D10S205 - D10S597 - D10S173 - D10S1199 - D10S530 - MXI1 - D10S88 - D10S168 - D10S554 - D10S1158 - (D10S562 - D10S531 - D10S1657 - D10S187 ) - D10S221 - D10S421 - D10S1236 - D10S503 - D10S610 - ADRA2B - ADRB1 - D10S190 - D10S542 - D10S1693 - D10S1785 - D10S209 ] - {D10S1483 - D10S587 - *D10S43}- D10S1723 - D10S12 - D10S216 - EMX2 EMX2 - D10S50 - D10S575 - FGFR2 - D10S217 - D10S590 - D10S36 - [D10S1134 - D10S555 - D10S6 - D10S212 - D10S25 - D10S169 ] - qter
Authors Fults(93), Rasheed (95), Albarosa (95), Zedenius (96), Maier (97),Mollenhauer (97),Nakamura (98),Safara (98),Yamakawa (98),Peiffer-Schneider (98)
Text [gliomas], (location of DMBT1 ), {DN} , * *:agressive bladder carcinoma
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY tumor suppressor
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • tumor suppressor gene(s)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   LOH    
    in astrocytoma anaplastic and glioblastoma multiform malignant melanoma in progression, follicular thyroid carcinoma in progession, endometrialcarcinoma
    tumoral   LOH    
    in metastatic lung carcinoma (small and squamous cell), upper respiratory tract carcinoma with poor prognosis, oral squamous cell carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS