Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TSEN15 contributors: mct - updated : 26-08-2016
HGNC name tRNA splicing endonuclease subunit 15
HGNC id 16791
Corresponding disease
PCH2F pontocerebellar hypoplasia 2F
Location 1q25.3      Physical location : 184.020.810 - 184.043.341
Genatlas name tRNA splicing endonuclease 15
Synonym name
  • chromosome 1 open reading frame 19
    • Synonym symbol(s) HSEN15, C1orf19, PCH2F, sen15
    DNA
    TYPE functioning gene
    STRUCTURE 45.64 kb     5 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 2010 - 175 - 2001 11318611
    5 - 1998 - 171 - 2001 11318611
    5 - 1894 - 134 - 2001 11318611
    5 - 1856 - 129 - 2001 11318611
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrainhindbraincerebellum   Homo sapiens
    Reproductivefemale systemuterus  highly
     male systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • involved in tRNA splicing, and impairing can be tolerated through development, but ultimately leads to the phenotypes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PCH2F
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS