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FLASH GENE
Symbol TRNT1 contributors: - updated : 29-10-2004
HGNC name tRNA nucleotidyl transferase, CCA-adding, 1
HGNC id 17341
Location 3p25.1      Physical location : 3.168.599 - 3.190.704
Synonym name
  • CGI-47 protein
  • mitochondrial CCA-adding tRNA-nucleotidyltransferase
    • Synonym symbol(s) MtCCA, CGI-47, CCA1
    EC.number 2.7.7.25
    DNA
    TYPE functioning gene
    STRUCTURE 23.00 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1865 - 405 - Augustin
    - - 2264 - 414 - Augustin
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer homomer , monomer , dimer
    HOMOLOGY
    interspecies homolog to murine Trnt1
    homolog to rattus LOC312616
    Homologene
    FAMILY tRNA nucleotidyltransferase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION adding a CCA sequence in 3' terminal of tRNA
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism nucleic
    signaling
    a component
    INTERACTION
    DNA
    RNA tRNA binding
    small molecule cofactor, nucleotide,
  • ATP, CTP binding
  • magnesium ion binding as a cofactor
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS